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Meers MP, Llagas G, Janssens DH, Codomo CA, Henikoff S

During the repair phase of late inflammation, M1 macrophages polarize toward M2 macrophages, secreting anti-inflammatory factors (including IL-4, IL-10, IL-13 and TGF-) to inhibit the inflammatory response and facilitate tissue repair and remodeling (Fig

Benfotiamine, a lipid-soluble thiamine derivative, is thought to inhibit three major diabetes-related pathways (hexosamine, AGE formation, and DAG-PKC pathways), which alter gene expression and protein function, causing vascular dysfunction, inflammation, and oxidative stress, all of which contribute to the pathogenesis of DPN

doi: 10.1038/s41564-023-01355-5

In milk and dairy products the methionine/cysteine ratio is around 3/1

Conclusion As we continue to learn more about Long COVID, its clear that a multifaceted approach to treatment is necessary