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Pediatric patients aged 8 to less than 10 years (n=41 at baseline) could titrate to a maximum dosage of 10 mg once daily, and pediatric patients aged 10 to 17 years could titrate to a maximum dosage of 20 mg once daily

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Could targeting the shared resistance mechanisms/targets of sorafenib and lenvatinib simultaneously reverse resistance to both drugs

C, combination study design

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