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When that happens, the molecule loses its biological activity

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( j ) Ponceau S staining (upper panel) and western blot (lower panel) detection of purified IgG and of serum with depleted IgG

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After cut into 46 m slices using a microtome, tissues were stained with hematoxylin and eosin (H&E) or Massons trichrome, imaged using a slice scanner (Pannoramic 250 FLASH, 3DHIESTECH, Hungary), and analyzed using the CaseViewer software

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