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Description
405 Following BiP dissociation, ATF6 is trafficked to the Golgi, where it undergoes sequential cleavage by Golgi-resident site 1 and site 2 proteases (S1P/MBTPS1 and S2P/MBTPS2, respectively), releasing a 50 kDa cleavage product that corresponds to the cytoplasmic half of ATF6 (referred to as ATF6p50 or ATF6-N [N = nuclear]), which subsequently translocates to the nucleus to mediate transcriptional regulation

Novel Debate-Style Cardiothoracic Surgery Journal Club: Results of a Pilot Curriculum

Strengthen the skin barrier and reduce sensitivity and redness

Serum values of proinflammatory cytokines are inversely correlated with serum leptin levels in patients with advanced stage cancer at different sites

Agarwal A, Sharma RK, Nallella KP, Thomas AJ Jr, Alvarez JG, Sikka SC

1999;26 Suppl 2:08
