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We have completed a proof-of-concept pilot study using this drug combination in children with severe TBIthe Pro-NAC Trial (ClinicalTrials.gov NCT01322009)

doi: 10.1007/s12011-015-0409-1

Apart from the globally diverse picture of nutritional deficiencies for thyroid trace element supply, accumulating information on the role of a genetic predisposition and polymorphic variations in the individual genetic makeup of the components of the thyroid hormone system (THS) shows the need for taking a new path towards a more personalized approach in preventive and therapeutic measures for thyroid hormone related diseases [13]

Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension