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Apart from the face, pigmentation can also affect the eye, the oral cavity, and the nasal mucous membranes

The effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: A double-blind crossover field study

Typical supplementation doses in clinical trials range from 3 to 5 grams daily, often divided into multiple doses, with treatment durations of 4-12 weeks

Overall, melanocortin peptides derived from POMC hold promise as future therapeutic options for OA, offering the potential to regulate inflammation and bone-related processes while minimizing side effects and maintaining immune function

[DOI] [PubMed] [Google Scholar] 29.Maizes V, Rakel D, Niemiec C