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As the causative bacteria die off due to antibiotics, inflammatory agents are released and temporarily worsen symptoms before improvement is noted

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A common approach is 8-12 weeks active, 8 weeks off, then reassess whether another cycle is needed

47 This drift correlates with reduced transcriptional coordination and increased expression variability, especially for ECM remodeling genes

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This information should be interpreted with a qualified provider to inform whether supplementation or lifestyle modifications warrant prioritynot to predict exact glutathione response