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Description
N Engl J Med 367: 817825, 2012
Many adults with obesity also suffer from other chronic diseases
It has been suggested to include up-regulation of growth factors [25], proangiogenic effect [26,27], and modulation of nitric oxide (NO) synthesis
Topical application (well-studied): Serums at 0.1-0.5%, creams at 0.2-1%, hair products at 0.1-0.3%
Soluble His-tagged GpoA protein was purified using nickel affinity chromatography following manufacturers instructions (Ni-NTA agarose, Qiagen)
Labs to run: CRP (inflammation), fasting glucose (peptides rarely affect but baseline helps), CMP for liver enzymes
