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Yinon Y, Visser J, Kelly EN, Windrim R, Amsalem H, Seaward PG, et al

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Grouping: Young control group, elderly control group, AOD 9604 group (500 g/kg/day), positive drug group (alendronate sodium, 10mg/kg/week)

Proteinligand interactions, including hydrogen bonds (distance cutoff 3.5 , angle 120), hydrophobic contacts, and -stacking interactions, were analyzed and visualized using PyMOL 2.5 (Schrdinger, 2023)