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It may also occur in people with certain fungal or protozoal infections and in people using other antimicrobial therapies such as herbs

Odell LR, Nilsson MT, Gising J, Lagerlund O, Muthas D, Nordqvist A, Karlen A, Larhed M: Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

In fact, a study analyzing the administration of anti-inflammatory glucocorticoids in cases of acute respiratory distress syndrome (ARDS) showed that hydrocortisone administration was followed by glutathione depletion and lower glutathione reductase activity in alveolar epithelial type II cells, thus failing to show beneficial effects [62]

The state of endothelial dysfunction is distinguished by a transition toward a pro-inflammatory state to diminished vasodilation and prothrombotic requirements, as well as a reduced ability to endure oxidative stress

Although its less common, people with vitamin B12 deficiency caused by a prolonged poor diet may be advised to stop taking the tablets once their vitamin B12 levels have returned to normal and their diet has improved

4.6.2 Proteostasis Protein homeostasis, or proteostasis, is essential for normal cellular function and involves maintaining proteins in appropriate conformation, concentration, and location within the cell [211]
