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The patient understands the need for regular (at least annual) review of treatment by the treating physician, preferably by a specialist experienced in the management of epilepsy, or mania or prophylaxis of migraine

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Encourage use of reminders for their birth control methods to avoid missing or late doses

Young, P., Finn, B

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However, possible mitotic segregation or indeed a loss of mtDNA mutation from mitotic tissues [17] means that if an mtDNA mutation is strongly suspected, then analysis of muscle mtDNA is recommended