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doi: 10.1038/nrd3031 211 PengHOuyangLLiDLiZYuanLFanLet al
Simic, T., Mimic-Oka, J., Ille, K., Dragicevic, D

Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways
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DISCUSSION The findings of our meta-analysis provide robust evidence for the efficacy and safety of the triple-hormone-receptor agonist retatrutide in obesity treatment

Therefore, this metabolic microenvironment of solid tumors can be recapitulated, and throughout the study we used 0.5 mM glucose in media to recapitulate glucose deprivation and, on top of this, added 20 mM lactic acid for a mimicry of lactic acidosis
