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As SLEs immune dysregulation is so complex and with the very real possibility of herb-drug and supplement-drug interactions, PK/PD studies are imperative (233)

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Follow-up testing in March 2018, which included a repeat comprehensive stool analysis (doctors data), confirmed the resolution of dysbiotic flora consistent with SIBO (Figure 1, Table 1, and Appendices C-M)

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Particularly relevant in the brain, arginase serves as a substrate for nitric oxide synthase, which produces nitric oxidean important cellular messenger (Wiesinger, 2001)