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10.1016/j.jhep.2009.11.030333333 37

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Furthermore, polyol pathway contributes to redox imbalance in diabetic tissues in oxidative stress via depletion of GSH in diabetic patients particularly type 1 DM.

Overall, the evidence in this section supports the view that amino acid metabolism does not merely provide energy and biosynthetic substrates, but instead shapes the functional spectrum of myeloid cells through several reusable network-level nodes

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