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It is not a drug, food, cosmetic, or dietary supplement, has not been evaluated by the FDA

B12 addition does not alter the dose calculation

however, the trial was powered to only detect much larger reductions

The metabolism of these vitamins depends largely on the type of vitamin administered

Methylcobalamin is often marketed as a 'natural' or 'bioactive' form, though evidence regarding superior efficacy compared to cyanocobalamin remains limited for most people

B12 is naturally present in animal based foods such as: Chicken and lean red meat Fish and seafood such as oysters, clams, salmon, tuna and catfish Dairy products such as milk, cheese, yoghurt, plus vegan milk substitutes that are fortified Eggs Plus, fortified breakfast cereals