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The absence of clear symptoms means that elevated B12 is usually detected incidentally during blood tests performed for other clinical indications

Exogenous Vascular Endothelial Growth Factor Delivery May Impair Tendon Healing Although VEGF and neovascularization may play a key role in the tendon healing process, the negative role of VEGF on ECM disruption cannot be ignored to some extent (as mentioned above for endogenous VEGF)

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A 2022 narrative review of double-blind, placebo-controlled trials administering 4 g/day of DHA reported mixed effects on blood pressure, with some trials showing no significant changes and others reporting reductions in systolic and diastolic blood pressure (35)