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Instead of targeting TAAs, UniCARs are engineered to recognize the human peptide sequence E5B9, also known as the UniCAR epitope, which is a fragment of the human nuclear autoantigen La/SS-B and absent in living cells (Jureczek et al., 2019)
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Both peptide and protein identifications were controlled at a 1% FDR cutoff using the target-decoy search approach
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doi: 10.1002/msc.1799
