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Special attention should be paid to potential interactions with drugs having anticholinergic properties

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During chronic alcohol consumption, increased ethanol concentrations induce the cytochrome P450 enzyme CYP2E1, which is present in both the endoplasmic reticulum and mitochondria, contributes to ethanol oxidation using reduced nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor, and generates superoxide anions, leading to the production of ROS and RNS [29]

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