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(I, C) Initiation of DAA therapy for HCV-negative recipients of an allograft from an HCV-viremic donor can occur prophylactically/preemptively (i.e., perioperatively without confirmation of HCV viremia in the recipient) or reactively after documentation of HCV viremia
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According to Centers for Disease Control and Prevention (CDC), as of May 2021, there have been over 3,700 cases of MIS-C in the United States, which has resulted in 35 deaths

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The median age at diagnosis is 47.1 years in the general population, whereas NF1-associated cases present significantly earlier, at 33.9 years
