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Pain reduction often appears first, followed by improved range of motion and reduced swelling

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The characteristic dermatological sign of vitamin B 12 deficiency is cutaneous pigmentation, which can be reversed by administration of vitamin B 12 .[4] Increased cutaneous pigmentation is especially accentuated in palmar creases, on the dorsa of hands and feet, in intertriginous areas, on oral mucosa and in recent scars

Some people also apply copper peptides for skin

I had a blurry spot in one eye which disappeared after a few weeks of injections

Some patients prefer magnesium chloride at 200 mg/cc (which can be more sedating) but most prefer magnesium sulfate at 500 mg/cc