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In ovarian or breast cancers, cyclodextrins may be used in combination with nanoparticles to provide controlled and targeted delivery of drugs, namely tamoxifen [204] or etoposide, to the tumor, thereby reducing the required systemic dose [205]

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Additionally, for ebselen to become a clinically acceptable radioprotector, there is also a need for establishing its selective radioprotective effects without compromising the tumor radiosensitivity