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Type 2 diabetes is far more common than type 1 and is mainly caused by acquired resistance to the effects of the hormone insulin , which facilitates removal of glucose from the blood
However, this robust inhibition did not affect the concentration of M0 C3 or total C3 acylcarnitine, suggesting that the contribution of valine catabolism to the pool of C3 acylcarnitine is limited by the low expression level of BCAT in plated human hepatocytes and that other substrates make key contributions to these distal pools of intermediates
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Alex J Med
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2018 Feb;25(4):3765-3774
