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It is commonly used to improve skin tone, reduce pigmentation, and boost the immune system
Nutrition 2004;20:590-3
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PUMA could be also downregulated by the overexpression of astrocytic micro-RNA (miR-29a), thus reducing neuronal vulnerability to ischemia (Ouyang et al., 2013)
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Nat Rev Immunol (2009) 9(3):16274
