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[53] studied the potential role of inflammatory, metabolic, liver damage, and iron metabolism mediators on the inverse association between HCC risk and coffee consumption, as suggested by the reduction in IL-6 levels, a biomarker of inflammation and innate immunity, together with reduced hepatocellular and cholestatic damage biomarkers, i.e., GLDH (glutamate dehydrogenase), ALT (alanine aminotransferase), AST (aspartate aminotransferase), GGT (-glutamyl transferase), and bilirubin

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doi: 10.1016/J.JAD.2021.04.035 192 SuhEChoARHaamJHGilMLeeYKKimYS