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Most formularies already had a slot for injectable GLP-1 receptor agonists

Ruenzi et al., 2005) and in experimental rat studies (see Seiwerth et al., 2018), a point recently confirmed (Xu et al., 2020)

The Phase 2 trial documented these side effects across all dose groups, and the data tells a clear story: most symptoms are gastrointestinal, most are mild to moderate, and most improve as the body adapts

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M., et al