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The Val allele, a product of this SNP, significantly reduces SOD2 activity within the mitochondria via the accelerated degradation of SOD2 Val mRNA

(2018) with a high dose of 1,000 mg/kg bw, show completely divergent results compared with all other studies cannot be explained, except that they used streptozotocin-induced diabetic rats

In peripheral tissues, they can be found in adipocytes, cardiomyocytes, and osteoblasts as they are essential for glucose-insulin homeostasis, gastrointestinal motility, cardiovascular health, inflammation, and tissue growth and repair (4)

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