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Restoration of Blood Total Glutathione Status and Lymphocyte Function Following Alpha-Lipoic Acid Supplementation in Patients with HIV Infection

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Although thioredoxin-(TRx-) and GSH-dependent pathways have overlapping functions in plants [117,118], Mhamdi and co-workers (2010) demonstrated no upregulation of TRx-dependent genes in increased H 2 O 2 conditions like cat2 and gr1cat2 , providing evidence that GR1 plays a specific role in intracellular H 2 O 2 metabolism