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Mechanistic Claims

Vitamin B12 absorption occurs primarily in the terminal ileum through intrinsic factor-mediated absorption (for both dietary and supplemental B12) and passive diffusion (particularly relevant for high-dose supplements)

Site rotation schedule Rotating injection sites prevents lipohypertrophy, a condition where repeated injections cause fatty tissue changes

Our approach aligns with 2025 guidelines from the American Society for Metabolic and Bariatric Surgery, emphasizing multimodal therapy for 10-15% body weight reduction over 12 weeks

But even when enough B12 is consumed, deficiency can emerge because of absorption issues

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