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Low total GSH and high homocysteine levels are considered as novel risk markers for acute stroke severity, and low total and reduced GSH levels may be potential risk markers for stroke severity and insufficient functional independence in large-artery atherosclerosis (157, 158)

Formal analysis was contributed by EC, SM, MD, AD, DL, GC, CL, VM, RG, FP, FCo, KA, and LB

Phase 2: Introduce AOD 9604 (weeks 5-8) Once tirzepatide is tolerated at the initial dose, add AOD 9604 at 250mcg daily