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Structural analysis suggests that LicoAs ,-unsaturated carbonyl moiety, characteristic of Michael acceptors, could modify Keap1 cysteine residues, thereby inhibiting Nrf2 ubiquitination and promoting its activation (Nakamura and Miyoshi, 2010)

Approach Overall skin dullness requires a holistic approach rather than a targeted one

However, at higher concentrations, there was no significant impact on tumor weight, indicating no off-target effects

These involve protein synthesis, metabolism of toxins, and immune function

10.1007/s13238-020-00755-1 Protein Cell 76 LjungK

However, stability of thiomers in solutions and gels is a major concern which may reduce the efficacy of thiomers