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(4) outcome measures, studies that used one or more of the following measurements were eligible: all-cause mortality, cardiovascular events, New York Heart Association (NYHA) classification, overall efficacy, exercise capacity (i.e., 6-minute walk), changes in cardiac function parameters (i.e., left ventricular ejection fraction (LVEF), strike volume (SV), cardiac output (CO), E/A, left ventricular end-systolic dimension (LVESD), left ventricular end-diastolic dimension (LVEDD), and left ventricular end-systolic volume (LVESV)), brain natriuretic peptide (BNP), N-terminal pro-brain natriuretic peptide (NT-proBNP), and adverse events

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