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Williamson E, Driver S, Baxter K, Al E
J Biol Rhythms 21(6):458469
But you've reduced effective dose by nearly half through timing alone
Notably, we found that the AC-like cell state is lost with serial passaging in patient derived cell models and xenografts, due to selection for more proliferative populations and due to transformation towards a mesenchymal phenotype
The goal was to significantly improve the ORR compared with the historical ORR of 29% achieved using conventional cytotoxic chemotherapies 9
One careful evaluation of the recipients of G6PD-deficient blood uncovered no deleterious consequences
