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Gels and creams containing 10-20% black seed oil have been tested for acne, eczema, and psoriasis with positive results and no serious side effects.2 9 42 While most people tolerate it well, there have been rare reports of severe allergic reactions sometimes just a rash on the skin, but occasionally a reaction that affected the whole body.46 47 If youre trying a topical for the first time, patch testing on a small area is a sensible precaution

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Keep the medication in its original pharmacy-labeled vial, as this serves as documentation

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doi: 10.1126/science.abm7949
