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When trying it for the first time, schedule 2 within 1 month (try 3 weeks apart) because it may need to build to a higher level before you feel these extraordinary effects

doi: 10.1096/fasebj.9.9.7601338

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Several potential mechanisms, mediated by mitochondria, that may lead to cell senescence include increased ROS production and elevations in damage-associated molecular patterns (DAMPs) leading to DNA damage response (DDR), which locks the cells in a senescence mode, leading to SASP