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Although excess Mn can activate microglia and promote neuroinflammation (Tjalkens et al., 2017), astrocytes may be the more dominant mediator of Mn neurotoxicity in the brain

But it is a sweet flavor, and the addition of menthol is a huge bonus

The study hypothesized that pro-inflammatory gut environment further promotes changes in microbiota (Yadav et al., 2023)

Elevated prenatal FRAA, especially when it is present in the mother or father, is associated with a heightened risk of childhood ASD

Kantarjian H, OBrien S, Keating MJ, Cortes J, Giles FJ, Beran M, Koller C, Andreeff M , Kornblau S, Pierce S, Murphy S, Freireich EJ

Folate and vitamin B12 are important cofactors of this mechanism, acting in the one-carbon metabolism