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Researchers believe this is due to increased ROS (increased oxidative stress) in the pancreatic beta cells.[ref] Related article : Type 2 Diabetes Genes Fatty liver disease: High homocysteine levels are associated with NAFLD (fatty liver disease, MAFLD)

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While the involvement of catalase in Parkinsons disease pathogenesis is evident, further investigations are required to dissect the precise molecular mechanisms underlying catalase dysregulation in PD and to pinpoint targeted therapeutic avenues

Pathogenesis and developing therapies Historically, cystinosis has been understood as a lysosomal storage disorder caused by cystine accumulation and subsequent lysosomal dysfunction
