glp 1 negative effects GLP-1 nausea: How to handle GLP-1s' most common side effect Struggling with GLP-1 therapy side

Examining trial-specific data is beyond the current scope, but we can gain summative insights from meta-analyses of these RCTs

Thus, new anti-obesity treatments are needed

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However, based also on small histopathologic studies that pointed to a marked expansion of the exocrine and endocrine pancreatic compartments with the use of incretin-based therapies, the former being accompanied by increased proliferation and dysplasia and the latter by -cell hyperplasia with the potential for evolution into neuroendocrine tumors [105], concerns remain [106], and monitoring for and reporting of pancreatic adverse effects will continue [104]

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[DOI] [PubMed] [Google Scholar] 91.Maselli D.B., Camilleri M