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This is a high response rate, especially considering these patients had already failed standard treatments

Inject the water slowly down the inside vial wall, swirl gently (do not shake), and refrigerate at 28 C

The difference between vial and pen storage primarily relates to air exposure: vials with unused doses can be re-capped and re-refrigerated between uses, while pens are single-use devices that must be discarded once opened, even if medication remains

Lyophilisation removes moisture from the material and helps support stability during storage and transport before research handling

Retrieved January 16, 2012

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