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PLoS One 2011;6:e26747

Among the causes suggested for CFS include damage to parts of the brain governing cognition, memory, mood, energy and perception, an altered stress response, an unbalanced immune system, a hidden chronic infection, excessive production of free radicals, reduced intracellular glutathione, abnormal sympathetic nervous system activity, cardiac dysfunction and others

Experimental Dermatology, 28 (3), 219-224

MOTs-C works by regulating mitochondrial energy

Dose escalation should be individualized, and patients should be counseled that the starting dose is not therapeutic for glycemic control but rather intended to reduce gastrointestinal adverse effects during treatment initiation