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Toxicity: Adverse effects to SAMe are rare but may include inappetence, vomiting, lethargy, and agitation after initial treatment

Plant Cell 10 , 11351149 (1998)

" Hepatitis B, Hepatitis C and HIV Transfusion-Transmitted Infections in the 21st Century." Vox Sang 100.1 (2011): 92-8

By contrast, OVA/LPS-based model has a complex immune response in the lung that not only enhances type 2 response including IL-13 but also involves type 1 response including IFN, and aberrant macrophage activation (2729), which better reflects the pathological changes in the lung during asthma exacerbation

[DOI] [PubMed] [Google Scholar] 682.Shibao C.A., Peche V.S., Pietka T.A., Samovski D., Williams I.M., Abumrad N.N., Gamazon E.R., Goldberg I.J., Wasserman D.H., Abumrad N.A

Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH