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Shiflett, 59 years, died on Saturday, August 22, 2015 in his home

Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

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Importantly, chronic periodontitis has been associated with elevated levels of inflammatory cytokines (e.g., IL-6, CRP), endothelial dysfunction, and accelerated atherogenesis, all of which overlap with the pathogenic effects of TMAO
