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Methods This is a cohort study combining several population-wide databases and covering a Spanish population of five million inhabitants, including all adults with obesity who initiated treatment with either GLP-1RA or SGLT-2i for type 2 diabetes from 2015 to 2021

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GLP-1 receptor agonists (GLP-1 RAs) with exenatide b.i.d

- **Curb appetite:** Helping individuals feel full, potentially leading to reduced food intake