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The researchers investigated how elevated glucose, fatty acids, and PCs affect glucose- and palmitate-induced apoptosis in INS-1E cells

Lactate orchestrates the TGF pathway and ferroptosis nexus in organ fibrosis via USP2 lactylation

Combining antioxidants with other therapeutic agents, such as anti-inflammatory drugs or targeted therapies, may offer synergistic effects in managing oxidative stress and related diseases

pKa=3.6) and 5-oxoprolinuria

doi: 10.1002/ptr.7965

Nitric oxide ultimately leads to the formation of RNS (reactive nitrogen species) which is known to cause mitochondrial damage and is therefore suggested to be a critical agent in chondrocyte function and apoptosis