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Matsuyama T, Yoshinaga SK, Shibue K, Mak TW (2021) Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-19

In many chronic diseases, the concentration of glutathione in the body is significantly reduced [1]

However, the structural diversity and reactivity of secondary metabolites suggest that some may form covalent bonds with cell wall polymers or proteins, especially under stress or during defense responses, but this is not well documented in the reviewed sources (Yang et al., 2018
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However, significantly positive effects of the biotics intervention on other markers of renal function, such as eGFR, serum albumin, C-reactive protein, IAA levels, and lipid metabolites, were not observed (Liu et al., 2022)

M.YaoG.SchiffrinE

10.1016/S1047-2797(01)00310-6 Ann
