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With respect to normal physiological functions, mast cells are known to regulate vasodilation, vascular homeostasis, innate and adaptive immune responses, angiogenesis, and venom detoxification

16 However, it is argued that this might lead to unnecessary intervention and could be limited to patients with moderate to severe symptoms

doi: 10.3390/ijms22105207 268 Martinez-OutschoornUELisantiMPSotgiaF

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