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Blood 131 , 25812593 (2018)

Disruption of proteostasis is now recognized as a unifying pathological hallmark linking neurodegenerative disorders, cancer, cardiovascular and metabolic diseases, and autoimmune conditions

Specifically, at the level 3 pathway within lipid metabolism, fatty acid degradation and glycerolipid metabolism were significantly enriched in the WKY group, whereas sphingolipid metabolism was significantly enriched in the ESC group (Fig

Similarly, knocking out ASL in TNBC cells leads to a delayed G 2 /M transition

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The appropriate treatment should prevent GERD from affecting a persons quality of life