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373 Given OPA1s role in mediating intercellular mitochondrial transfer via MDVs, 187 the ability to secrete damaged mitochondria into the extracellular space might be impaired in ADOA

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Differentiating from Other Conditions Neurological signs and symptoms can be vitamin B12 deficiency associated or due to other causes such as: Pernicious anemia Syphilis Neurosyphilis Human immunodeficiency virus (HIV)-associated vacuolar myelopathy Toxic neuropathies Tropical myeloneuropathy Your healthcare provider can make a proper diagnosis based on your symptoms, medical history, physical exam, and laboratory test findings

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References Phillips TG, Slomiany WP, Allison R

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However, these methods are still in the research phase

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