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Availability of data and materials Data described in the manuscript will be available upon request and approval by the UK Biobank ( Declarations Ethics approval and consent to participate This research has been conducted using the UK Biobank Resource under application number 42468 and other large studies and consortia providing publicly available summary statistics

Methods: Retrospective study

Excessive adrenergic stimulation induced by caffeine and other stimulant ingredients of EDs also leads to hyperglycemia and hypokalemia, which affects central nervous system function

Body mass index, lipid profile, fasting plasma glucose, hemoglobin A1c, prevalence of type 2 diabetes (DM), hypertension (HTN), and metabolic syndrome were higher in males than females, but FLI showed no significant difference

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J Cell Biochem 120:94099420 Maguire MJ, Hemming K, Hutton JL, Marson AG (2008) Reporting and analysis of open-label extension studies of anti-epileptic drugs