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R., Kato, A

397 While some of the notable responses sparked by such heat sensing are behavioral (e.g., seeking a cooler area) or largely supracellular (vasodilation, sweating, arrector pili relaxation), 397 evidence from model organisms indicates that HSF1 signaling may be upstream and/or downstream of noncell-autonomous regulation of the HSR in heterotypic tissues (i.e., signaling between different tissues)

Naqvi K, Jabbour E, Skinner J, Yilmaz M, Ferrajoli A, Bose P, Thompson P, Alvarado Y, Jain N, Takahashi K, Burger J, Estrov Z, Borthakur G , Pemmaraju N, Paul S, Cortes J, Kantarjian HM

It frequently coexists with sweating in other areas, particularly the soles (plantar hyperhidrosis) and underarms (axillary hyperhidrosis)

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