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Persistent cough should be evaluated rather than automatically attributed to Lyme disease
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Insulin resistance The brains high sensitivity to insulin is underscored by the abundance of insulin receptors in the hippocampus [210], where insulin signaling regulates synaptic plasticity, neurogenesis, and cognitive function through pathways such as PI3K/AKT, GSK3, and mTOR [211]

doi:10.4103/jrms.JRMS_644_16

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Microsatellite instability was reportedly significantly higher in RA synovial tissues than in osteoarthritis (OA) synovial tissues, indicating a decreased DNA mismatch repair (MMR) capacity and severe DNA damage
